William T Mahle Selected Research

Norwood Procedures

1/2022	Developmental Care Practice and Documentation Variability in the Cardiac ICU.
1/2018	Heart failure after the Norwood procedure: An analysis of the Single Ventricle Reconstruction Trial.
1/2016	Association of Digoxin With Interstage Mortality: Results From the Pediatric Heart Network Single Ventricle Reconstruction Trial Public Use Dataset.
1/2016	Outcomes of heart transplantation in children with hypoplastic left heart syndrome previously palliated with the Norwood procedure.
5/2012	Early developmental outcome in children with hypoplastic left heart syndrome and related anomalies: the single ventricle reconstruction trial.
12/2010	Prenatal diagnosis and risk factors for preoperative death in neonates with single right ventricle and systemic outflow obstruction: screening data from the Pediatric Heart Network Single Ventricle Reconstruction Trial(∗).
5/2009	Postoperative cerebral oxygenation in hypoplastic left heart syndrome after the Norwood procedure.
11/2006	Freedom from neoaortic insufficiency: a comparison of classic Norwood and Norwood-Sano procedures.
3/2006	Elastic properties of the reconstructed aorta in hypoplastic left heart syndrome.
1/2006	Relationship of surgical approach to neurodevelopmental outcomes in hypoplastic left heart syndrome.

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William T Mahle Research Topics

Disease

19	Congenital Heart Defects (Congenital Heart Defect) 01/2022 - 12/2004
17	Hypoplastic Left Heart Syndrome 10/2022 - 02/2002
16	Heart Failure 01/2022 - 05/2005
7	Heart Diseases (Heart Disease) 10/2020 - 05/2003
6	Infections 01/2022 - 05/2007
6	Tetralogy of Fallot (Fallot Tetralogy) 01/2019 - 04/2009
5	Heart Arrest (Cardiac Arrest) 01/2022 - 05/2005
4	Ventricular Heart Septal Defects (Ventricular Septal Defect) 01/2022 - 12/2003
4	Fibrosis (Cirrhosis) 01/2021 - 01/2009
3	Brain Injuries (Brain Injury) 01/2022 - 01/2016
3	Aortic Coarctation 01/2019 - 04/2009
3	Inflammation (Inflammations) 06/2015 - 01/2005
3	Birth Weight (Birth Weights) 02/2013 - 07/2002
3	Cardiomyopathies (Cardiomyopathy) 09/2011 - 08/2007
2	Acute Coronary Syndrome 11/2017 - 02/2012
2	Necrotizing Enterocolitis 11/2017 - 08/2014
2	Ischemia 02/2012 - 08/2004
2	Myocarditis (Carditis) 02/2012 - 05/2009
1	Pain (Aches) 01/2022
1	End Stage Liver Disease 01/2021
1	Ascites 01/2021
1	Splenomegaly 01/2021
1	Vascular Remodeling 01/2021
1	Atrioventricular Septal Defect 01/2021
1	Liver Diseases (Liver Disease) 01/2021
1	Thrombocytopenia (Thrombopenia) 01/2021
1	Varicose Veins (Varicose Vein) 01/2021
1	Diabetes Mellitus 01/2019
1	Pulmonary Vein Stenosis 01/2018
1	Bacterial Infections (Bacterial Infection) 09/2017
1	Hemolysis 01/2017
1	Hypoxia (Hypoxemia) 12/2016
1	Cardiac Sudden Death (Sudden Cardiac Arrest) 04/2016
1	Hyperglycemia 12/2015
1	Arteriosclerosis 12/2015
1	Hyperplasia 12/2015
1	Aortic Valve Insufficiency (Aortic Regurgitation) 01/2015
1	Bicuspid Aortic Valve Disease 01/2015
1	Traumatic Brain Injuries (Traumatic Brain Injury) 12/2014
1	Brain Ischemia (Cerebral Ischemia) 12/2014
1	Hemorrhage 08/2014
1	Disease Progression 03/2014
1	Portal Hypertension 10/2013
1	Acute Kidney Injury (Acute Renal Failure) 09/2013
1	Enterocolitis 08/2013
1	Restrictive Cardiomyopathy 05/2013
1	Chest Pain (Chest Pains) 02/2012
1	Pericarditis 02/2012
1	Lymphopenia (Lymphocytopenia) 06/2010

Drug/Important Bio-Agent (IBA)

3	Brain Natriuretic Peptide (Natrecor)FDA Link 11/2008 - 09/2005
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2019
2	Endothelin-1 (Endothelin 1)IBA 07/2008 - 07/2004
1	cytidylyl-(3'-5')-cytidine (CpC)IBA 10/2022
1	Cell-Free Nucleic AcidsIBA 01/2022
1	Coenzyme A (CoA)IBA 01/2019
1	SteroidsIBA 01/2019
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2019
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 11/2017
1	Adrenergic Receptors (Adrenergic Receptor)IBA 11/2017
1	Sirolimus (Rapamycin)FDA Link 04/2017
1	Hydroxyurea (Hydrea)FDA LinkGeneric 12/2016
1	N(6)-allyl-N(6)-cyclohexyladenosineIBA 04/2016
1	Complement System Proteins (Complement)IBA 04/2016
1	AS 8IBA 01/2016
1	Digoxin (Digitek)FDA LinkGeneric 01/2016
1	Lymphocyte Function-Associated Antigen-1 (LFA-1)IBA 12/2015
1	SugarsIBA 12/2015
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2015
1	ApolipoproteinsIBA 12/2014
1	Apolipoproteins E (ApoE)IBA 12/2014
1	CytokinesIBA 03/2014
1	TroponinIBA 02/2012
1	Warfarin (Coumadin)FDA LinkGeneric 12/2011
1	Erythropoietin FDA Link 11/2011
1	SodiumIBA 06/2010
1	CreatinineIBA 06/2010

Therapy/Procedure

18	Heart Transplantation (Grafting, Heart) 01/2022 - 05/2003
17	Therapeutics 10/2022 - 05/2003
12	Norwood Procedures 01/2022 - 07/2002
10	Transplantation 01/2022 - 05/2003
7	Extracorporeal Membrane Oxygenation 01/2018 - 07/2002
5	Heart-Assist Devices 01/2022 - 07/2002
5	Length of Stay 10/2020 - 02/2002
5	Fontan Procedure (Fontan Operation) 09/2016 - 02/2002
3	Cardiopulmonary Bypass (Heart-Lung Bypass) 06/2015 - 08/2004
3	Artificial Respiration (Mechanical Ventilation) 08/2014 - 09/2011
2	Cardiopulmonary Resuscitation (CPR) 11/2017 - 06/2009
2	Mechanical Ventilators (Ventilator) 09/2017 - 02/2012
2	Blood Transfusion (Blood Transfusions) 12/2016 - 10/2007
2	Sternotomy 10/2015 - 02/2012
2	Erythrocyte Transfusion 08/2014 - 08/2014
2	Perioperative Period 02/2013 - 08/2003
2	Radiofrequency Ablation 10/2008 - 03/2008
1	Right Heart Bypass (Cavopulmonary Anastomosis) 01/2021
1	Arterial Switch Operation 01/2021
1	Transjugular Intrahepatic Portasystemic Shunt 01/2017
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 12/2016
1	Blalock-Taussig Procedure 01/2016
1	Enteral Nutrition (Feeding, Tube) 08/2013
1	Cardiac Surgical Procedures 02/2013